產(chǎn)品中心/ products

      您的位置:首頁  -  產(chǎn)品中心  -  天然產(chǎn)物  -  天然產(chǎn)物對照品標(biāo)準(zhǔn)品  -  右旋畢扣扣靈堿(荷包牡丹堿)

      右旋畢扣扣靈堿(荷包牡丹堿)

      • 產(chǎn)品型號:
      • 更新時間:2016-08-18

      簡要描述:(+)-Bicuculline(D-Bicuculline;NSC 32192) CAS:485-49-4 右旋畢靈堿(荷包牡丹堿)
      Description:Pale yellow crystalline powder
      Purity(HPLC):min.99.0%

      產(chǎn)品詳情

      (+)-Bicuculline(D-Bicuculline;NSC 32192) CAS:485-49-4  右旋畢靈堿(荷包牡丹堿)
      Description:Pale yellow crystalline powder 
      Purity(HPLC):min.99.0%

      Classical GABAA antagonist (+)-Bicuculline(D-Bicuculline;NSC 32192) CAS:485-49-4

      Product Name: (+)-Bicuculline;D-Bicuculline
      Synonyms: D-Bicuculline;(R-(R*,S*))-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-furo(3,4-e)-1,3-benzodioxol-8(6H)-one; (6R)-6-[(5S)-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one; 6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[4,3-g][1,3]benzodioxol-8-one; (5S)-6-methyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium; (S)-6-((S)-5,6,7,8-Tetrahydro-6-methyl-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuro[4,5-d][1,3]dioxol-8(6H)-one
      CAS No.: 485-49-4
      Molecular Formula: C20H17NO6
      Molecular Weight: 367.36
      Occurrence: Found in Dicentra cucullaria (L.) Bernh., Adlumia fungosa (Ait.) Greene, Fumariaceae, and several Corydalis species.
      Appearance: Elongated plates from chloroform-menthanol or pale yellow crystalline powder
      Solubility: Soluble in benzene, chloroform, ethyl acetate. Sparingly soluble in alcohol and ether,practically not in water.
      Purity by HPLC: >99%

      Biological Description: (+)-Bicuculline is GABAA receptor antagonist

      Applications:  Alkaloid naturally occurring in the d-form. Shows GABA antagonist activity.

        Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons. These receptors are the major targets for benzodiazepines and related anxiolytic drugs. Bicuculline is a competitive GABAA receptor antagonist that can act as an allosteric inhibitor at GABAA receptors.At 100 μM, it blocks spontaneously opening chloride channels in the outside-out patches from the cultured cortical neurons. Bicuculline also reversibly blocks GABAA receptors on horizontal cells in the mouse retina with an IC50 value of 1.7 μM.By blocking the inhibitory action of GABA, bicuculline mimics the action of epilepsy and is widely used in experimental studies as a convulsant, inducing seizure in hippocampal or cortical neurons in prepared brain slices.

      在線咨詢

      留言框

      • 產(chǎn)品:

      • 您的單位:

      • 您的姓名:

      • 聯(lián)系電話:

      • 常用郵箱:

      • 省份:

      • 詳細地址:

      • 補充說明:

      • 驗證碼:

        請輸入計算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7
      產(chǎn)品中心
      天然產(chǎn)物

      CONTACT

      辦公地址:中國(上海)自由貿(mào)易試驗區(qū)臨港新片區(qū)新楊公路1666號3幢315室 EMAIL:2885066715@qq.com
      掃碼關(guān)注公眾號
      版權(quán)所有©2025 凱立德生物醫(yī)藥技術(shù)(上海)有限公司 All Rights Reserved   備案號:滬ICP備15046197號-1   sitemap.xml技術(shù)支持:化工儀器網(wǎng)   管理登陸

      TEL:021-58180488

      掃碼關(guān)注公眾號
      主站蜘蛛池模板: 久久精品综合一区二区三区| 精品一区狼人国产在线| 久久久久人妻精品一区| 国产日韩精品一区二区在线观看播放| 国产精品亚洲一区二区三区在线| 影音先锋中文无码一区| 国产成人久久精品一区二区三区 | 精品人妻少妇一区二区三区在线| 亚洲综合av一区二区三区| 高清一区二区三区日本久| 日韩精品无码视频一区二区蜜桃| 国产一区二区精品久久岳√ | 久久一区二区三区免费| 国产乱子伦一区二区三区| 精品国产一区二区三区AV| 国产一区二区三区影院| 亚洲午夜一区二区三区| 国产精品久久久久久麻豆一区| 一区二区三区国产精品| 性无码免费一区二区三区在线| 国产精品视频一区二区三区四| 三上悠亚国产精品一区| 中文字幕一区视频一线| 好爽毛片一区二区三区四| 中文字幕一区在线播放| 国产日韩精品一区二区三区在线| 国产韩国精品一区二区三区| 国产伦精品一区二区三区视频金莲| 日本免费精品一区二区三区| 一本色道久久综合一区| 成人区人妻精品一区二区不卡网站| 国产天堂一区二区综合| 国精无码欧精品亚洲一区| 亚洲国产精品自在线一区二区| 亚洲视频一区在线播放| 好吊妞视频一区二区| 一区二区在线免费视频| 精品福利一区二区三| 精品午夜福利无人区乱码一区| 糖心vlog精品一区二区三区| 日本一区午夜爱爱|